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Department of Justice/ Drug Enforcement Administration

I'm a big proponent of delaying caffeine intake 90 to 120 minutes after waking because when you wake up, you have an increase in body temperature that's healthy, an increase in a corticosteroid called cortisol, which is a healthy increase

Pro-oxidant effect Despite its well-documented antioxidant role, it is known that depending on the context, UA can act as pro-oxidant, including during its biosynthesis

The gut microbiota-metabolite axis plays a significant role in early renal function decline, with protein fermentation products closely correlated with renal function parameters (103)